Induction of cell-associated chemokines after endotoxin administration to healthy humans.

نویسندگان

  • D P Olszyna
  • E De Jonge
  • P E Dekkers
  • S J van Deventer
  • T van der Poll
چکیده

Erythrocytes express the Duffy antigen receptor for chemokines. Endotoxin injection into humans induced high levels of interleukin-8 (IL-8), growth-related oncogene alpha, and monocyte chemoattractant protein 1 in circulating erythrocytes. IL-8 was also recovered from mononuclear and polymorphonuclear cells. Cell-associated chemokines may more accurately reflect their production than plasma concentrations.

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عنوان ژورنال:
  • Infection and immunity

دوره 69 4  شماره 

صفحات  -

تاریخ انتشار 2001